What is the adult inhaled dose of Ipratropium (Atrovent)?

• A. 1-2 mg
• B. 0.25-0.5 mg
• C. 0.05 mg
• D. 0.75 mg

Answer: (B)

Ipra­tropium is a small-dose bronchodilator given by inhalation to relieve bronchospasm. For adults, the effective per-dose amount is in the mid‑tenths of a milligram range. The usual nebulized dose is 0.5 mg per administration, and some protocols allow as low as 0.25 mg for lighter adults or initial dosing. This dosing keeps the drug localized in the lungs to block acetylcholine’s action on muscarinic receptors, producing bronchodilation while minimizing systemic effects. Doses much higher than this per single dose, such as 1–2 mg or 0.75 mg, are not typical and increase the risk of side effects; doses as low as 0.05 mg would likely be ineffective. Therefore, an adult inhaled dose that falls within 0.25–0.5 mg is the appropriate range.