What is the adult and pediatric dose of pralidoxime in the NAAK autoinjector?

• A. 2 mg IM
• B. 600 mg IM
• C. 10 mg IV
• D. 100 mg PO

Answer: (B)

In nerve agent or organophosphate exposure, pralidoxime (2-PAM) is given to reactivate acetylcholinesterase and help reverse the toxic effects. The NAAK autoinjector provides a fixed dose of pralidoxime of 600 mg delivered intramuscularly, designed for rapid administration in the field. This fixed IM dose is used for both adults and pediatric patients because the device is built for quick, uncomplicated delivery without weight-based calculations, which is crucial in time‑sensitive emergencies. The other options don’t reflect how the autoinjector delivers pralidoxime: the 2 mg IM figure is an atropine dose, not pralidoxime; a small IV dose or an oral dose isn’t compatible with the autoinjector’s route or purpose.

So, the adult and pediatric dose of pralidoxime in the NAAK autoinjector is 600 mg given intramuscularly.